Copy number variation in fetal alcohol spectrum disorder
نویسندگان
چکیده
منابع مشابه
Copy-number variation in the pathogenesis of autism spectrum disorder.
Autism spectrum disorder is a neurodevelopmental disorder present in 1% of the population, characterized by impairments in reciprocal social interaction, communication deficits and restricted patterns of behavior. Approximately 10% of the autism spectrum disorder population is thought to have large chromosomal rearrangements. Copy-number variations (CNV) alter the genome structure either by dup...
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BACKGROUND Fetal alcohol spectrum disorder is a range of disabilities caused by gestational exposure to alcohol. FASD is the leading cause of preventable mental retardation and developmental disability in the United States, with an incidence of 1-10 per 1000 live births. FASD in Israel has yet to be examined systematically. OBJECTIVES To evaluate professionals' experience, awareness and knowl...
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Background: Baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5) gene is an inhibitor of apoptosis that expresses in human embryonic tissues but it is absent in most healthy adult tissues. The copy number of BIRC5 has been indicated to be highly increased in tumor tissues; however, its association with the age of onset in breast cancer is not well understood. Methods: Forty tumor tiss...
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Prenatal alcohol exposure produces a multitude of detrimental alcohol-induced defects in children collectively known as fetal alcohol spectrum disorder (FASD). Children with FASD often exhibit delayed or abnormal mental, neural, and physical growth. Socioeconomic status, race, genetics, parity, gravidity, age, smoking, and alcohol consumption patterns are all factors that may influence FASD. Op...
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Maternal alcohol use during pregnancy can have deleterious effects. Alcohol in the mother’s blood passes through the placenta to the embryo and fetus via the umbilical cord, and may cause numerous problems, including developmental delays, growth impairment, and a variety of behavioral changes [1]. Compared to all other substances of abuse, including heroin, cocaine, and marijuana, alcohol produ...
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ژورنال
عنوان ژورنال: Biochemistry and Cell Biology
سال: 2018
ISSN: 0829-8211,1208-6002
DOI: 10.1139/bcb-2017-0241